Medera Clinic

Instagram Facebook Youtube
Make an Appointment

Use of Exosomes for Dry Eye Syndrome

What is an Exosome?

Exosomes are nano-sized cellular messenger vesicles containing growth factors, cytokines, and microRNAs secreted by cells, especially stem cells. They are known for their cell regeneration-supporting and anti-inflammatory properties.

Mechanism of Action of Exosome in Dry Eye

Exosome therapy aims to improve tear balance by supporting the repair of damaged tissues on the eye surface:

  • Reduces ocular surface inflammation

  • Supports the function of lacrimal glands

  • Accelerates corneal epithelial regeneration

  • Can reduce the effects of Meibomian gland dysfunction

  • Supports the formation of a protective barrier on the eye surface

Application Methods

1. Topical (Drop) Exosome Application

  • It is the most commonly used method

  • Prepared in a sterile, preservative-free form

  • Applied directly to the eye surface

  • Preferred especially for mild to moderate dry eye

2. Periocular (Around the Eye) Injection

  • In severe cases or chronic conditions

  • In the form of microinjection into the tissues around the eye

  • Must be applied by a specialist physician

In Which Types of Dry Eye Can It Be Used?

  • Evaporative dry eye

  • Meibomian gland dysfunction (MGD)

  • Non-Sjogren’s dry eye

  • Screen use and age-related dry eye

  • Dry eye developing after LASIK

  • Contact lens-related dry eye

Advantages

  • Non-surgical

  • Provides a more regenerative effect compared to medications

  • Can provide long-term relief

  • Supports natural cellular repair mechanisms

Treatment Duration and Number of Sessions

  • Effect is usually observed within 2–4 weeks

  • 1–3 courses may be recommended (according to the clinical picture)

  • Can be combined with other treatments (artificial tears, IPL, warm compress)

Safety and Things to Know

Exosome therapy:

  • Is considered an experimental / supportive treatment

  • Does not replace standard treatments on its own

  • Application must be performed under the supervision of an ophthalmologist

  • FDA/EMA approved indication scope is still limited

Who Is It Not Suitable For?

  • Those with active eye infection

  • Early period after intraocular surgery

  • Patients with autoimmune disease in the active phase

  • Pregnancy and breastfeeding period (requires doctor evaluation)

Diğer Yazılar